In general, the technique is best used for submicron particles and can be used to measure particle with sizes less than a nanometer. Examples include determining nanogold size, protein size, latex size, and colloid size. In addition, Kalliope™ is fully compliant with the US FDA's 21 CFR part 11 regulations. Applications for Dynamic Light Scattering DLS is most commonly used to analyze nanoparticles. A DLS instrument was adapted to withstand the accelerations in a drop tower, and a liquid handling set-up was connected in order to stabilize the liquid temperature and enable rapid cooling or heating. We used dynamic light scattering (DLS) to quantify the mobility of nanoparticles on ground and in microgravity. Dynamic light scattering provides insight into the dynamic properties of soft materials by measuring single scattering events, meaning that each detected photon has been scattered by the sample exactly once. Kalliope™ provides an intuitive one-page workflow, where input parameters, measurements and analyses are all at hand. Gravity affects colloidal dispersions via sedimentation and convection. Transmittance gives you instant feedback about your sample, and allows automatic optimization of measurement parameters (angle, focus position, and measurement duration). Several different particle sizes in a single suspension can be precisely resolved, thanks to highly developed algorithms in the firmware.Ĭontinuous transmittance measured automatically Particle-size measurements: Unprecedented resolution The Brownian motion (diffusion coefficient) of the particles in a liquid is determined and a hydrodynamic particle diameter is obtained via the Stokes-Einstein equation. In this paper, we apply and discuss modulated 3D. Development of a Standard Method for Nanoparticle Sizing by Using the Angular Dependence of Dynamic Light Scattering. It is particularly suitable for the characterization of nanomaterials. Dynamic light scattering (DLS) is a versatile tool for sizing nanoparticles (NPs) suspended in fluids. We have created a one-page workflow, where input parameters, results and analysis are all on a single page: You can set up your experiments in a few seconds, and produce the analyses and reports you need at the touch of a button. Evaluation of the uncertainty in the measurement of nanoparticle size by dynamic light scattering. Dynamic Light Scattering is a widely used method for particle size measurement. It determines particle size by measuring dynamic light scattering (DLS).Ī highlight of the Litesizer™ 100 is its ingeniously simple software. The Litesizer™ 100 is an instrument for characterizing nano- and microparticles in dispersions and solutions. Particle analysis at the touch of a button

Dynamic light scattering nanoparticle